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Discovery of New Pyrrolo[2,3-d]pyrimidine Derivatives as Potential Multi-Targeted Kinase Inhibitors and Apoptosis Inducers

In the pursuit of developing more potent and effective targeted kinase inhibitors (TKIs), a series of new compounds, specifically halogenated ‘(E)-4-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N’-benzylidenebenzohydrazides’, were successfully synthesized in three steps with high yields. Among these nov...

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Detalles Bibliográficos
Autores principales: Alotaibi, AbdulAziz A., Alanazi, Mohammed M., Rahman, A. F. M. Motiur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536928/
https://www.ncbi.nlm.nih.gov/pubmed/37765132
http://dx.doi.org/10.3390/ph16091324