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NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy

INTRODUCTION: Spinal muscular atrophy (SMA) is a fatal neurodegenerative disorder, characterized by motor neuron (MN) degeneration and severe muscular atrophy and caused by Survival of Motor Neuron (SMN) depletion. Therapies aimed at increasing SMN in patients have proven their efficiency in allevia...

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Detalles Bibliográficos
Autores principales: El Khoury, Mirella, Biondi, Olivier, Bruneteau, Gaelle, Sapaly, Delphine, Bendris, Sabrina, Bezier, Cynthia, Clerc, Zoé, Akar, Elias Abi, Weill, Laure, Eid, Assaad A., Charbonnier, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536974/
https://www.ncbi.nlm.nih.gov/pubmed/37780204
http://dx.doi.org/10.3389/fncel.2023.1242828