Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity

The spread of Human Immunodeficiency Virus (HIV) still represents a global public health issue of major concern, and would benefit from unveiling unique viral features as targets for drug design. In this respect, HIV-1 integrase (IN), due to the absence of homologs in human cells, is a popular targe...

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Detalles Bibliográficos
Autores principales: Tocco, Graziella, Canton, Serena, Laus, Antonio, Caboni, Pierluigi, Le Grice, Stuart F. J., Tramontano, Enzo, Esposito, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537185/
https://www.ncbi.nlm.nih.gov/pubmed/37764476
http://dx.doi.org/10.3390/molecules28186700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537185/
https://www.ncbi.nlm.nih.gov/pubmed/37764476
http://dx.doi.org/10.3390/molecules28186700

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