Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of substituted isatins 1a–b, a number of α-amino acids 2a–e and (E)-2-aryl-1-nitroethenes 3a–e in a chemo/regio-selective manner using [3+2] cycloaddition (Huisgen) reaction under microwave irradiation conditions....

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Detalles Bibliográficos
Autores principales: Sharma, Richa, Yadav, Lalit, Nasim, Ali Adnan, Yadav, Ravi Kant, Chen, Rui Hong, Kumari, Neha, Ruiqi, Fan, Sharon, Ashoke, Sahu, Nawal Kishore, Ippagunta, Sirish Kumar, Coghi, Paolo, Wong, Vincent Kam Wai, Chaudhary, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537280/
https://www.ncbi.nlm.nih.gov/pubmed/37764279
http://dx.doi.org/10.3390/molecules28186503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537280/
https://www.ncbi.nlm.nih.gov/pubmed/37764279
http://dx.doi.org/10.3390/molecules28186503

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