Synthesis and Evaluation of (99m)Tc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms. To develop novel (99m)Tc-labelled hypoxia imaging radiotracers, in this study, five isocyan...

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Detalles Bibliográficos
Autores principales: Ruan, Qing, Liu, Yitong, Liao, Lihao, Hao, Jinyu, Jiang, Yuhao, Jiang, Jianyong, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537343/
https://www.ncbi.nlm.nih.gov/pubmed/37765084
http://dx.doi.org/10.3390/ph16091276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537343/
https://www.ncbi.nlm.nih.gov/pubmed/37765084
http://dx.doi.org/10.3390/ph16091276

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