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Development of Large Hollow Particles for Pulmonary Delivery of Cyclosporine A

The purpose of this study was to prepare large hollow particles (LHPs) by spray drying for pulmonary delivery of cyclosporine A (CsA), using L-Leucine (LEU) and hydroxypropyl methylcellulose (HPMC) as excipients and ammonium bicarbonate (AB) as a porogen. The prepared LHPs were spherical particles c...

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Detalles Bibliográficos
Autores principales: Huang, Yongpeng, Tang, Hui, Meng, Xiangyan, Zhao, Zitong, Liu, Yanli, Liu, Dongxin, Chen, Bo, Zou, Zhiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537410/
https://www.ncbi.nlm.nih.gov/pubmed/37765173
http://dx.doi.org/10.3390/pharmaceutics15092204