Long-Term Survival and Induction of Operational Tolerance to Murine Islet Allografts by Co-Transplanting Cyclosporine A Microparticles and CTLA4-Ig

One strategy to prevent islet rejection is to create a favorable immune-protective local environment at the transplant site. Herein, we utilize localized cyclosporine A (CsA) delivery to islet grafts via poly(lactic-co-glycolic acid) (PLGA) microparticles to attenuate allograft rejection. CsA-elutin...

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Detalles Bibliográficos
Autores principales: Kuppan, Purushothaman, Wong, Jordan, Kelly, Sandra, Lin, Jiaxin, Worton, Jessica, Castro, Chelsea, Paramor, Joy, Seeberger, Karen, Cuesta-Gomez, Nerea, Anderson, Colin C., Korbutt, Gregory S., Pepper, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537425/
https://www.ncbi.nlm.nih.gov/pubmed/37765170
http://dx.doi.org/10.3390/pharmaceutics15092201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537425/
https://www.ncbi.nlm.nih.gov/pubmed/37765170
http://dx.doi.org/10.3390/pharmaceutics15092201

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