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Intracellular Fate of the Photosensitizer Chlorin e4 with Different Carriers and Induced Metabolic Changes Studied by (1)H NMR Spectroscopy

Porphyrinic photosensitizers (PSs) and their nano-sized polymer-based carrier systems are required to exhibit low dark toxicity, avoid side effects, and ensure high in vivo tolerability. Yet, little is known about the intracellular fate of PSs during the dark incubation period and how it is affected...

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Detalles Bibliográficos
Autores principales: Vermathen, Martina, Kämpfer, Tobias, Nuoffer, Jean-Marc, Vermathen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537485/
https://www.ncbi.nlm.nih.gov/pubmed/37765292
http://dx.doi.org/10.3390/pharmaceutics15092324