Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol

Following the contraindication of codeine use in children, increasing use of tramadol has been observed in pain management protocols. However, tramadol’s pharmacokinetics (PK) and pharmacodynamics are influenced by cytochrome P450 (CYP)2D6 activity, similarly to codeine. Previous studies in adults h...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodieux, Frédérique, Storelli, Flavia, Curtin, François, Manzano, Sergio, Gervaix, Alain, Posfay-Barbe, Klara M., Desmeules, Jules, Daali, Youssef, Samer, Caroline F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537526/
https://www.ncbi.nlm.nih.gov/pubmed/37765034
http://dx.doi.org/10.3390/ph16091227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537526/
https://www.ncbi.nlm.nih.gov/pubmed/37765034
http://dx.doi.org/10.3390/ph16091227

Ejemplares similares