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Synthesis, DFT Study, and In Vitro Evaluation of Antioxidant Properties and Cytotoxic and Cytoprotective Effects of New Hydrazones on SH-SY5Y Neuroblastoma Cell Lines

A series of ten new hydrazide–hydrazone derivatives bearing a pyrrole ring were synthesized and structurally elucidated through appropriate spectral characteristics. The target hydrazones were assessed for radical scavenging activity through 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-...

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Detalles Bibliográficos
Autores principales: Tzankova, Diana, Kuteva, Hristina, Mateev, Emilio, Stefanova, Denitsa, Dzhemadan, Alime, Yordanov, Yordan, Mateeva, Alexandrina, Tzankova, Virginia, Kondeva-Burdina, Magdalena, Zlatkov, Alexander, Georgieva, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537553/
https://www.ncbi.nlm.nih.gov/pubmed/37765006
http://dx.doi.org/10.3390/ph16091198