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Isolation of ACE2-dependent and -independent sarbecoviruses from Chinese horseshoe bats

While the spike proteins from severe acute respiratory syndrome coronaviruses-1 and 2 (SARS-CoV and SARS-CoV-2) bind to host angiotensin-converting enzyme 2 (ACE2) to infect cells, the majority of bat sarbecoviruses cannot use ACE2 from any species. Despite their discovery almost 20 years ago, ACE2-...

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Detalles Bibliográficos
Autores principales: Guo, Hua, Li, Ang, Dong, Tian-Yi, Si, Hao-Rui, Hu, Ben, Li, Bei, Zhu, Yan, Shi, Zheng-Li, Letko, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537568/
https://www.ncbi.nlm.nih.gov/pubmed/37655938
http://dx.doi.org/10.1128/jvi.00395-23