Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis

Multiple sclerosis is a disease caused by autoantigen-responsive immune cells that disrupt the myelin in the central nervous system (CNS). Although immunosuppressive drugs are used to suppress symptoms, no definitive therapy exists. As in the experimental autoimmune encephalitis (EAE) model of multi...

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Detalles Bibliográficos
Autores principales: Gomi, Masaki, Nakayama, Yuka, Sakurai, Yu, Oyama, Ryotaro, Iwasaki, Koki, Doi, Mizuki, Liu, Yi, Hori, Mizuho, Watanabe, Himeka, Hashimoto, Kohei, Tanaka, Hiroki, Tange, Kota, Nakai, Yuta, Akita, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537621/
https://www.ncbi.nlm.nih.gov/pubmed/37765078
http://dx.doi.org/10.3390/ph16091270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537621/
https://www.ncbi.nlm.nih.gov/pubmed/37765078
http://dx.doi.org/10.3390/ph16091270

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