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Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis
Multiple sclerosis is a disease caused by autoantigen-responsive immune cells that disrupt the myelin in the central nervous system (CNS). Although immunosuppressive drugs are used to suppress symptoms, no definitive therapy exists. As in the experimental autoimmune encephalitis (EAE) model of multi...
Autores principales: | Gomi, Masaki, Nakayama, Yuka, Sakurai, Yu, Oyama, Ryotaro, Iwasaki, Koki, Doi, Mizuki, Liu, Yi, Hori, Mizuho, Watanabe, Himeka, Hashimoto, Kohei, Tanaka, Hiroki, Tange, Kota, Nakai, Yuta, Akita, Hidetaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537621/ https://www.ncbi.nlm.nih.gov/pubmed/37765078 http://dx.doi.org/10.3390/ph16091270 |
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