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Intertumoral heterogeneity impacts oncolytic vesicular stomatitis virus efficacy in mouse pancreatic cancer cells

Oncolytic virus (OV) therapy is a promising virus-based approach against various malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studies demonstrated that human PDAC cell lines are highly variable in their permissiveness to OVs. Mouse PDAC cell lines, which are widely u...

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Detalles Bibliográficos
Autores principales: Goad, Dakota W., Nesmelova, Anna Y., Yohe, Laurel R., Grdzelishvili, Valery Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537684/
https://www.ncbi.nlm.nih.gov/pubmed/37671865
http://dx.doi.org/10.1128/jvi.01005-23