Copper-Catalyzed Intramolecular Olefinic C(sp(2))–H Amidation for the Synthesis of γ-Alkylidene-γ-lactams

Herein, we report the copper-catalyzed dehydrogenative C(sp(2))–N bond formation of 4-pentenamides via nitrogen-centered radicals. This reaction provides a straightforward and efficient preparation method for γ-alkylidene-γ-lactams. Notably, we could controllably synthesize α,β-unsaturated- or α,β-s...

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Detalles Bibliográficos
Autores principales: Nozawa-Kumada, Kanako, Hayashi, Masahito, Kwon, Eunsang, Shigeno, Masanori, Yada, Akira, Kondo, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537769/
https://www.ncbi.nlm.nih.gov/pubmed/37764458
http://dx.doi.org/10.3390/molecules28186682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537769/
https://www.ncbi.nlm.nih.gov/pubmed/37764458
http://dx.doi.org/10.3390/molecules28186682

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