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The Antiviral Factor SERINC5 Impairs the Expression of Non-Self-DNA

SERINC5 is a restriction factor that becomes incorporated into nascent retroviral particles, impairing their ability to infect target cells. In turn, retroviruses have evolved countermeasures against SERINC5. For instance, the primate lentiviruses (HIV and SIV) use Nef, Moloney Murine Leukemia Virus...

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Detalles Bibliográficos
Autores principales: Shi, Yuhang, Simpson, Sydney, Ahmed, Shahad K., Chen, Yuexuan, Tavakoli-Tameh, Aidin, Janaka, Sanath Kumar, Evans, David T., Serra-Moreno, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537789/
https://www.ncbi.nlm.nih.gov/pubmed/37766367
http://dx.doi.org/10.3390/v15091961