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Unconjugated Multi-Epitope Peptides Adjuvanted with ALFQ Induce Durable and Broadly Reactive Antibodies to Human and Avian Influenza Viruses

An unconjugated composite peptide vaccine targeting multiple conserved influenza epitopes from hemagglutinin, neuraminidase, and matrix protein and formulated with a safe and highly potent adjuvant, Army Liposome formulation (ALFQ), generated broad and durable immune responses in outbred mice. The a...

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Detalles Bibliográficos
Autores principales: Rikhi, Nimisha, Sei, Clara J., Rao, Mangala, Schuman, Richard F., Kroscher, Kellie A., Matyas, Gary R., Muema, Kevin, Lange, Camille, Assiaw-Dufu, Aba, Hussin, Elizabeth, Jobe, Ousman, Alving, Carl R., Fischer, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537791/
https://www.ncbi.nlm.nih.gov/pubmed/37766144
http://dx.doi.org/10.3390/vaccines11091468