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Broadly neutralizing antibody epitopes on HIV-1 particles are exposed after virus interaction with host cells

The envelope (Env) glycoproteins on HIV-1 virions are the sole target of broadly neutralizing antibodies (bNAbs) and the focus of vaccines. However, many cross-reactive conserved epitopes are often occluded on virus particles, contributing to the evasion of humoral immunity. This study aimed to iden...

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Detalles Bibliográficos
Autores principales: Rao, Priyanka Gadam, Lambert, Gregory S., Upadhyay, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537810/
https://www.ncbi.nlm.nih.gov/pubmed/37681958
http://dx.doi.org/10.1128/jvi.00710-23