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Exploring the role of macrophages in the progression from atypical hyperplasia to endometrial carcinoma through single-cell transcriptomics and bulk transcriptomics analysis

INTRODUCTION: In this study, we aimed to identify key genes in endometrial cancer by conducting single-cell analysis of macrophages. METHODS: We sourced clinical data from the TCGA database as well as supplementary datasets GSE201926 and GSE173682. Using bulk-seq data of atypical endometrial hyperpl...

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Detalles Bibliográficos
Autores principales: Song, Xiaolei, Na, Re, Peng, Nianghai, Cao, Wenming, Ke, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537943/
https://www.ncbi.nlm.nih.gov/pubmed/37780629
http://dx.doi.org/10.3389/fendo.2023.1198944