Meta-analysis of senescent cell secretomes to identify common and specific features of the different senescent phenotypes: a tool for developing new senotherapeutics

DNA damage resulting from genotoxic injury can initiate cellular senescence, a state characterized by alterations in cellular metabolism, lysosomal activity, and the secretion of factors collectively known as the senescence-associated secretory phenotype (SASP). Senescence can have beneficial effect...

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Detalles Bibliográficos
Autores principales: Oguma, Yo, Alessio, Nicola, Aprile, Domenico, Dezawa, Mari, Peluso, Gianfranco, Di Bernardo, Giovanni, Galderisi, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537976/
https://www.ncbi.nlm.nih.gov/pubmed/37770897
http://dx.doi.org/10.1186/s12964-023-01280-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537976/
https://www.ncbi.nlm.nih.gov/pubmed/37770897
http://dx.doi.org/10.1186/s12964-023-01280-4

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