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Patulin Stimulates Progenitor Leydig Cell Proliferation but Delays Its Differentiation in Male Rats during Prepuberty

Patulin is a mycotoxin with potential reproductive toxicity. We explored the impact of patulin on Leydig cell (LC) development in male rats. Male Sprague Dawley rats (21 days postpartum) were gavaged patulin at doses of 0.5, 1, and 2 mg/kg/day for 7 days. Patulin markedly lowered serum testosterone...

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Detalles Bibliográficos
Autores principales: Li, Huitao, Su, Ming, Lin, Hang, Li, Jingjing, Wang, Shaowei, Ye, Lei, Li, Xingwang, Ge, Renshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538017/
https://www.ncbi.nlm.nih.gov/pubmed/37756007
http://dx.doi.org/10.3390/toxins15090581