Development of a New Cell-Based AP-1 Gene Reporter Potency Assay for Anti-Anthrax Toxin Therapeutics

Anthrax toxin is a critical virulence factor of Bacillus anthracis. The toxin comprises protective antigen (PA) and two enzymatic moieties, edema factor (EF) and lethal factor (LF), forming bipartite lethal toxin (LT) and edema toxin (ET). PA binds cellular surface receptors and is required for intr...

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Detalles Bibliográficos
Autores principales: Ouyang, Weiming, Xie, Tao, Fang, Hui, Frucht, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538138/
https://www.ncbi.nlm.nih.gov/pubmed/37755954
http://dx.doi.org/10.3390/toxins15090528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538138/
https://www.ncbi.nlm.nih.gov/pubmed/37755954
http://dx.doi.org/10.3390/toxins15090528

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