Bioactivity-Guided Synthesis: In Silico and In Vitro Studies of β-Glucosidase Inhibitors to Cope with Hepatic Cytotoxicity

The major cause of hyperglycemia can generally be attributed to β-glucosidase as per its involvement in non-alcoholic fatty liver disease. This clinical condition leads to liver carcinoma (HepG2 cancer). The phthalimides and phthalamic acid classes possess inhibitory potential against glucosidase, f...

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Detalles Bibliográficos
Autores principales: Khushal, Aneela, Farooq, Umar, Khan, Sara, Rasul, Azhar, Wani, Tanveer A., Zargar, Seema, Shahzad, Sohail Anjum, Bukhari, Syed Majid, Khan, Nazeer Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538174/
https://www.ncbi.nlm.nih.gov/pubmed/37764324
http://dx.doi.org/10.3390/molecules28186548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538174/
https://www.ncbi.nlm.nih.gov/pubmed/37764324
http://dx.doi.org/10.3390/molecules28186548

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