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Design and preclinical testing of an anti‐CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia

Acute megakaryoblastic leukaemia (AMkL) is a rare subtype of acute myeloid leukaemia (AML) representing 5% of all reported cases, and frequently diagnosed in children with Down syndrome. Patients diagnosed with AMkL have low overall survival and have poor outcome to treatment, thus novel therapies s...

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Detalles Bibliográficos
Autores principales: Tigu, Adrian Bogdan, Constantinescu, Catalin Sorin, Teodorescu, Patric, Kegyes, David, Munteanu, Raluca, Feder, Richard, Peters, Mareike, Pralea, Ioana, Iuga, Cristina, Cenariu, Diana, Marcu, Andra, Tanase, Alina, Colita, Anca, Drula, Rares, Bergthorsson, Jon Thor, Greiff, Victor, Dima, Delia, Selicean, Cristina, Rus, Ioana, Zdrenghea, Mihnea, Gulei, Diana, Ghiaur, Gabriel, Tomuleasa, Ciprian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538266/
https://www.ncbi.nlm.nih.gov/pubmed/37667538
http://dx.doi.org/10.1111/jcmm.17810