OPA1 deficiency impairs oxidative metabolism in cycling cells, underlining a translational approach for degenerative diseases

Dominant optic atrophy is an optic neuropathy with varying clinical symptoms and progression. A severe disorder is associated with certain OPA1 mutations and includes additional symptoms for >20% of patients. This underscores the consequences of OPA1 mutations in different cellular populations, n...

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Detalles Bibliográficos
Autores principales: Millet, Aurélie M. C., Coustham, Corentin, Champigny, Camille, Botella, Marlène, Demeilliers, Christine, Devin, Anne, Galinier, Anne, Belenguer, Pascale, Bordeneuve-Guibé, Joel, Davezac, Noélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538295/
https://www.ncbi.nlm.nih.gov/pubmed/37497665
http://dx.doi.org/10.1242/dmm.050266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538295/
https://www.ncbi.nlm.nih.gov/pubmed/37497665
http://dx.doi.org/10.1242/dmm.050266

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