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Efficient mapping of accurate long reads in minimizer space with mapquik

DNA sequencing data continue to progress toward longer reads with increasingly lower sequencing error rates. We focus on the critical problem of mapping, or aligning, low-divergence sequences from long reads (e.g., Pacific Biosciences [PacBio] HiFi) to a reference genome, which poses challenges in t...

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Detalles Bibliográficos
Autores principales: Ekim, Bariş, Sahlin, Kristoffer, Medvedev, Paul, Berger, Bonnie, Chikhi, Rayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538364/
https://www.ncbi.nlm.nih.gov/pubmed/37399256
http://dx.doi.org/10.1101/gr.277679.123