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Whole Slide Imaging-Based Prediction of TP53 Mutations Identifies an Aggressive Disease Phenotype in Prostate Cancer

In prostate cancer, there is an urgent need for objective prognostic biomarkers that identify the metastatic potential of a tumor at an early stage. While recent analyses indicated TP53 mutations as candidate biomarkers, molecular profiling in a clinical setting is complicated by tumor heterogeneity...

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Detalles Bibliográficos
Autores principales: Pizurica, Marija, Larmuseau, Maarten, Van der Eecken, Kim, de Schaetzen van Brienen, Louise, Carrillo-Perez, Francisco, Isphording, Simon, Lumen, Nicolaas, Van Dorpe, Jo, Ost, Piet, Verbeke, Sofie, Gevaert, Olivier, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538366/
https://www.ncbi.nlm.nih.gov/pubmed/37352385
http://dx.doi.org/10.1158/0008-5472.CAN-22-3113