Impact of antiretroviral therapy intensification with C-C motif chemokine receptor 5 antagonist maraviroc on HIV-associated neurocognitive impairment

OBJECTIVES: Chemokine receptor CCR5 is the principal co-receptor for entry of M-tropic HIV virus into immune cells. It is expressed in the central nervous system and may contribute to neuro-inflammation. The CCR5 antagonist maraviroc (MVC) has been suggested to improve HIV-associated neurocognitive...

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Detalles Bibliográficos
Autores principales: Shikuma, Cecilia M., Wojna, Valerie, De Gruttola, Victor, Siriwardhana, Chathura, Souza, Scott A., Rodriguez-Benitez, Rosa J., Turner, Emilee H., Kallianpur, Kalpana, Bolzenius, Jacob, Chow, Dominic, Matos, Miriam, Shiramizu, Bruce, Clements, Danielle M., Premeaux, Thomas A., Ndhlovu, Lishomwa C., Paul, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538417/
https://www.ncbi.nlm.nih.gov/pubmed/37418541
http://dx.doi.org/10.1097/QAD.0000000000003650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538417/
https://www.ncbi.nlm.nih.gov/pubmed/37418541
http://dx.doi.org/10.1097/QAD.0000000000003650

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