Cargando…

Impact of antiretroviral therapy intensification with C-C motif chemokine receptor 5 antagonist maraviroc on HIV-associated neurocognitive impairment

OBJECTIVES: Chemokine receptor CCR5 is the principal co-receptor for entry of M-tropic HIV virus into immune cells. It is expressed in the central nervous system and may contribute to neuro-inflammation. The CCR5 antagonist maraviroc (MVC) has been suggested to improve HIV-associated neurocognitive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shikuma, Cecilia M., Wojna, Valerie, De Gruttola, Victor, Siriwardhana, Chathura, Souza, Scott A., Rodriguez-Benitez, Rosa J., Turner, Emilee H., Kallianpur, Kalpana, Bolzenius, Jacob, Chow, Dominic, Matos, Miriam, Shiramizu, Bruce, Clements, Danielle M., Premeaux, Thomas A., Ndhlovu, Lishomwa C., Paul, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538417/ https://www.ncbi.nlm.nih.gov/pubmed/37418541 http://dx.doi.org/10.1097/QAD.0000000000003650

Ejemplares similares

Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation
por: Gangcuangco, Louie Mar A., et al.
Publicado: (2020)

Correction: Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation
por: Gangcuangco, Louie Mar A., et al.
Publicado: (2021)

Neurocognitive Trajectories After 72 Weeks of First-Line Anti-retroviral Therapy in Vietnamese Adults With HIV-HCV Co-infection
por: Paul, Robert H., et al.
Publicado: (2021)

Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection
por: D'Antoni, Michelle L., et al.
Publicado: (2019)

Frailty Characteristics in Chronic HIV Patients are Markers of White Matter Atrophy Independently of Age and Depressive Symptoms: A Pilot Study
por: Kallianpur, Kalpana J., et al.
Publicado: (2016)

Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial
por: van Lelyveld, Steven F. L., et al.
Publicado: (2015)

Impact of Cannabis Use on Brain Structure and Function in Suppressed HIV Infection
por: Kallianpur, Kalpana J., et al.
Publicado: (2020)

The latent HIV reservoir: current advances in genetic sequencing approaches
por: Moar, Preeti, et al.
Publicado: (2023)

Effect of Maraviroc Intensification on HIV-1-Specific T Cell Immunity in Recently HIV-1-Infected Individuals
por: Kawana-Tachikawa, Ai, et al.
Publicado: (2014)

Role of Natural Killer Cells in HIV-Associated Malignancies
por: Leal, Fabio E., et al.
Publicado: (2017)

Maraviroc intensification for HIV-1-positive immunological non-responders (INRs) despite virological suppression during HAART
por: Rusconi, S, et al.
Publicado: (2010)

Maraviroc as Intensification Strategy in HIV-1 Positive Patients with Deficient Immunological Response: an Italian Randomized Clinical Trial
por: Rusconi, Stefano, et al.
Publicado: (2013)

High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy
por: Gangcuangco, Louie Mar A., et al.
Publicado: (2016)

Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification
por: Ananworanich, Jintanat, et al.
Publicado: (2015)

Maraviroc Intensification Improves Endothelial Function in Abacavir-Treated Patients, an Open-Label Randomized Cross-Over Pilot Study
por: Krikke, Maaike, et al.
Publicado: (2016)

Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment
por: de Menezes, Erika G. Marques, et al.
Publicado: (2022)

Maraviroc Intensification Modulates Atherosclerotic Progression in HIV-Suppressed Patients at High Cardiovascular Risk. A Randomized, Crossover Pilot Study
por: Francisci, Daniela, et al.
Publicado: (2019)

Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed Therapies
por: Premeaux, Thomas A., et al.
Publicado: (2022)

Relationship between Circulating Inflammatory Monocytes and Cardiovascular Disease Measures of Carotid Intimal Thickness
por: SahBandar, Ivo N., et al.
Publicado: (2020)

Mucosal-homing natural killer cells are associated with aging in persons living with HIV
por: Kroll, Kyle W., et al.
Publicado: (2022)

Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy
por: Zungsontiporn, Nath, et al.
Publicado: (2016)

Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection
por: Yeung, Stephen T., et al.
Publicado: (2022)

High Virologic Failure Rates with Maraviroc-Based Salvage Regimens Among Indian Patients: A Preliminary Analysis—Maraviroc Effectiveness in HIV-1 Subtype C
por: Pujari, Sanjay, et al.
Publicado: (2018)

Monocytes Expand with Immune Dysregulation and Is Associated with Insulin Resistance in Older Individuals with Chronic HIV
por: Shikuma, Cecilia M., et al.
Publicado: (2014)

ELEVATED CIRCULATING MONOCYTES AND MONOCYTE ACTIVATION IN PULMONARY POSTACUTE SEQUELAE OF SARS-COV-2 INFECTION
por: PARK, JUWON, et al.
Publicado: (2022)

Failure of combined antiretroviral therapy intensification with maraviroc and raltegravir in chronically HIV-1 infected patients to reduce the viral reservoir: the IntensHIV randomized trial
por: Lafeuillade, Alain, et al.
Publicado: (2014)

Cytotoxic chemotherapy reduces T cell trafficking to the spleen by downregulating the expression of C-C motif chemokine ligand 21 and C-C motif chemokine ligand 19
por: Liu, Lina, et al.
Publicado: (2018)

Maraviroc in the treatment of HIV infection
por: Ray, Neelanjana
Publicado: (2009)

Potentials of C‐C motif chemokine 2–C‐C chemokine receptor type 2 blockers including propagermanium as anticancer agents
por: Yumimoto, Kanae, et al.
Publicado: (2019)

Next-Generation Human Cerebral Organoids as Powerful Tools To Advance NeuroHIV Research
por: Premeaux, Thomas A., et al.
Publicado: (2021)

Inter-platform concordance of gene expression data for the prediction of chemical mode of action
por: Siriwardhana, Chathura, et al.
Publicado: (2016)

Chemokine (C-X-C motif) ligand 1/chemokine (C-X-C motif) receptor 2 autocrine loop contributes to cellular proliferation, migration and apoptosis in cervical cancer
por: Sun, Jiping, et al.
Publicado: (2022)

Use of maraviroc in patients with undetectable viral load: efficacy, tolerance and predictors of viral response in MARAVIROC-cohort study
por: Jesús Pérez Elías, María, et al.
Publicado: (2014)

Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
por: Feng, Siqi, et al.
Publicado: (2015)

Host Genetic Factors Predisposing to HIV-Associated Neurocognitive Disorder
por: Kallianpur, Asha R., et al.
Publicado: (2014)

The Significance of Selected C-C Motif Chemokine Ligands in Colorectal Cancer Patients
por: Zajkowska, Monika, et al.
Publicado: (2022)

Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model
por: MA, TENG, et al.
Publicado: (2015)

2164: Emotional dysfunction and stigma: Its effects on HIV-associated neurocognitive disorders (HAND)
por: Aponte, Michell R., et al.
Publicado: (2018)

Elevation of Non-Classical (CD14(+/low)CD16(++)) Monocytes Is Associated with Increased Albuminuria and Urine TGF-β(1) in HIV-Infected Individuals on Stable Antiretroviral Therapy
por: Mitchell, Brooks I., et al.
Publicado: (2016)

Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa
por: Siddik, Abu Bakar, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3k2p6f9cno9ga84jnrg8e2pori