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Entropy predicts sensitivity of pseudorandom seeds

Seed design is important for sequence similarity search applications such as read mapping and average nucleotide identity (ANI) estimation. Although k-mers and spaced k-mers are likely the most well-known and used seeds, sensitivity suffers at high error rates, particularly when indels are present....

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Detalles Bibliográficos
Autores principales: Maier, Benjamin Dominik, Sahlin, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538493/
https://www.ncbi.nlm.nih.gov/pubmed/37217253
http://dx.doi.org/10.1101/gr.277645.123