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Entropy predicts sensitivity of pseudorandom seeds
Seed design is important for sequence similarity search applications such as read mapping and average nucleotide identity (ANI) estimation. Although k-mers and spaced k-mers are likely the most well-known and used seeds, sensitivity suffers at high error rates, particularly when indels are present....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538493/ https://www.ncbi.nlm.nih.gov/pubmed/37217253 http://dx.doi.org/10.1101/gr.277645.123 |