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Therapeutic role of interleukin-1 receptor antagonist in pancreatic diseases: mendelian randomization study

BACKGROUND: The interleukin-1 pathway has been linked to pancreatic diseases. We applied the Mendelian randomization approach to explore whether higher interleukin-1 receptor antagonist (IL-1RA) levels reduce the risk of acute and chronic pancreatitis and pancreatic cancer. METHODS: Genetic variants...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Miao, Yuyang, Ruan, Xixian, Chen, Jie, Li, Xue, Larsson, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538534/
https://www.ncbi.nlm.nih.gov/pubmed/37781392
http://dx.doi.org/10.3389/fimmu.2023.1240754