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Multimodal Imaging for Validation and Optimization of Ion Channel-Based Chemogenetics in Nonhuman Primates

Chemogenetic tools provide an opportunity to manipulate neuronal activity and behavior selectively and repeatedly in nonhuman primates (NHPs) with minimal invasiveness. Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are one example that is based on mutated muscarinic acetylchol...

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Detalles Bibliográficos
Autores principales: Hori, Yuki, Nagai, Yuji, Hori, Yukiko, Oyama, Kei, Mimura, Koki, Hirabayashi, Toshiyuki, Inoue, Ken-ichi, Fujinaga, Masayuki, Zhang, Ming-Rong, Takada, Masahiko, Higuchi, Makoto, Minamimoto, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538582/
https://www.ncbi.nlm.nih.gov/pubmed/37620158
http://dx.doi.org/10.1523/JNEUROSCI.0625-23.2023