Cargando…
Review and further developments in statistical corrections for Winner’s Curse in genetic association studies
Genome-wide association studies (GWAS) are commonly used to identify genomic variants that are associated with complex traits, and estimate the magnitude of this association for each variant. However, it has been widely observed that the association estimates of variants tend to be lower in a replic...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538662/ https://www.ncbi.nlm.nih.gov/pubmed/37721937 http://dx.doi.org/10.1371/journal.pgen.1010546 |