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The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells
Multidrug resistance (MDR) is a major obstacle to successful cancer chemotherapy. A typical form of MDR is due to the overexpression of membrane transport proteins., such as Glycoprotein-P (P-gp), resulting in an increased drug efflux preventing drug cytotoxicity. P-gp is mainly localized on the pla...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538702/ https://www.ncbi.nlm.nih.gov/pubmed/37768946 http://dx.doi.org/10.1371/journal.pone.0285834 |