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The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells

Multidrug resistance (MDR) is a major obstacle to successful cancer chemotherapy. A typical form of MDR is due to the overexpression of membrane transport proteins., such as Glycoprotein-P (P-gp), resulting in an increased drug efflux preventing drug cytotoxicity. P-gp is mainly localized on the pla...

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Detalles Bibliográficos
Autores principales: Henry, Aubery, Mauperin, Marine, Devy, Jerome, Dedieu, Stephane, Chazee, Lise, Hachet, Cathy, Terryn, Christine, Duca, Laurent, Martiny, Laurent, Devarenne-Charpentier, Emmanuelle, Btaouri, Hassan El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538702/
https://www.ncbi.nlm.nih.gov/pubmed/37768946
http://dx.doi.org/10.1371/journal.pone.0285834