Cargando…
The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells
Multidrug resistance (MDR) is a major obstacle to successful cancer chemotherapy. A typical form of MDR is due to the overexpression of membrane transport proteins., such as Glycoprotein-P (P-gp), resulting in an increased drug efflux preventing drug cytotoxicity. P-gp is mainly localized on the pla...
Autores principales: | Henry, Aubery, Mauperin, Marine, Devy, Jerome, Dedieu, Stephane, Chazee, Lise, Hachet, Cathy, Terryn, Christine, Duca, Laurent, Martiny, Laurent, Devarenne-Charpentier, Emmanuelle, Btaouri, Hassan El |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538702/ https://www.ncbi.nlm.nih.gov/pubmed/37768946 http://dx.doi.org/10.1371/journal.pone.0285834 |
Ejemplares similares
-
Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells
por: Courageot, Marie-Pierre, et al.
Publicado: (2020) -
Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons
por: Verzeaux, Laurie, et al.
Publicado: (2017) -
LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion
por: Langlois, Benoit, et al.
Publicado: (2022) -
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
por: Thevenard, Jessica, et al.
Publicado: (2014) -
Identification of LRP-1 as an endocytosis and recycling receptor for β1-integrin in thyroid cancer cells
por: Theret, Louis, et al.
Publicado: (2017)