Peroxisome proliferator-activated receptor γ activation ameliorates liver fibrosis—differential action of transcription factor EB and autophagy on hepatocytes and stellate cells

BACKGROUND: Peroxisome proliferator-activated receptor γ (PPARγ) activation suppresses HSC activation and liver fibrosis. Moreover, autophagy is implicated in hepatic lipid metabolism. Here, we determined whether PPARγ activation ameliorates HSC activation by downregulating transcription factor EB (...

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Detalles Bibliográficos
Autores principales: Yum, Yunjin J., Yoo, Jin, Bang, Kyuhoon, Jun, Ji Eun, Jeong, In-Kyung, Ahn, Kyu Jeung, Chung, Ho Yeon, Hwang, You-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538880/
https://www.ncbi.nlm.nih.gov/pubmed/37204406
http://dx.doi.org/10.1097/HC9.0000000000000154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538880/
https://www.ncbi.nlm.nih.gov/pubmed/37204406
http://dx.doi.org/10.1097/HC9.0000000000000154

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