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Peroxisome proliferator-activated receptor γ activation ameliorates liver fibrosis—differential action of transcription factor EB and autophagy on hepatocytes and stellate cells
BACKGROUND: Peroxisome proliferator-activated receptor γ (PPARγ) activation suppresses HSC activation and liver fibrosis. Moreover, autophagy is implicated in hepatic lipid metabolism. Here, we determined whether PPARγ activation ameliorates HSC activation by downregulating transcription factor EB (...
Autores principales: | Yum, Yunjin J., Yoo, Jin, Bang, Kyuhoon, Jun, Ji Eun, Jeong, In-Kyung, Ahn, Kyu Jeung, Chung, Ho Yeon, Hwang, You-Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538880/ https://www.ncbi.nlm.nih.gov/pubmed/37204406 http://dx.doi.org/10.1097/HC9.0000000000000154 |
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