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The Molecular Basis of Wnt/β-Catenin Signaling Pathways in Neurodegenerative Diseases

Defective Wnt signaling is found to be associated with various neurodegenerative diseases. In the canonical pathway, the Frizzled receptor (Fzd) and the lipoprotein receptor-related proteins 5/6 (LRP5/LRP6) create a seven-pass transmembrane receptor complex to which the Wnt ligands bind. This intera...

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Detalles Bibliográficos
Autores principales: Anand, Ananya Anurag, Khan, Misbah, V, Monica, Kar, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539095/
https://www.ncbi.nlm.nih.gov/pubmed/37780577
http://dx.doi.org/10.1155/2023/9296092