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The Molecular Basis of Wnt/β-Catenin Signaling Pathways in Neurodegenerative Diseases
Defective Wnt signaling is found to be associated with various neurodegenerative diseases. In the canonical pathway, the Frizzled receptor (Fzd) and the lipoprotein receptor-related proteins 5/6 (LRP5/LRP6) create a seven-pass transmembrane receptor complex to which the Wnt ligands bind. This intera...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539095/ https://www.ncbi.nlm.nih.gov/pubmed/37780577 http://dx.doi.org/10.1155/2023/9296092 |