Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets

Complete or partial deletions of chromosome 7 (-7/del7q) belong to the most frequent chromosomal abnormalities in myeloid neoplasm (MN) and are associated with a poor prognosis. The disease biology of -7/del7q and the genes responsible for the leukemogenic properties have not been completely elucida...

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Detalles Bibliográficos
Autores principales: Mori, Minako, Kubota, Yasuo, Durmaz, Arda, Gurnari, Carmelo, Goodings, Charnise, Adema, Vera, Ponvilawan, Ben, Bahaj, Waled S., Kewan, Tariq, LaFramboise, Thomas, Meggendorfer, Manja, Haferlach, Claudia, Barnard, John, Wlodarski, Marcin, Visconte, Valeria, Haferlach, Torsten, Maciejewski, Jaroslaw P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539177/
https://www.ncbi.nlm.nih.gov/pubmed/37634012
http://dx.doi.org/10.1038/s41375-023-02003-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539177/
https://www.ncbi.nlm.nih.gov/pubmed/37634012
http://dx.doi.org/10.1038/s41375-023-02003-x

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