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Evolution of hypoxia and hypoxia-inducible factor asparaginyl hydroxylase regulation in chronic kidney disease

BACKGROUND: The roles of hypoxia and hypoxia inducible factor (HIF) during chronic kidney disease (CKD) are much debated. Interventional studies with HIF-α activation in rodents have yielded contradictory results. The HIF pathway is regulated by prolyl and asparaginyl hydroxylases. While prolyl hydr...

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Detalles Bibliográficos
Autores principales: Faivre, Anna, Dissard, Romain, Kuo, Willy, Verissimo, Thomas, Legouis, David, Arnoux, Grégoire, Heckenmeyer, Carolyn, Fernandez, Marylise, Tihy, Matthieu, Rajaram, Renuga D, Delitsikou, Vasiliki, Le, Ngoc An, Spingler, Bernhard, Mueller, Bert, Shulz, Georg, Lindenmeyer, Maja, Cohen, Clemens, Rutkowski, Joseph M, Moll, Solange, Scholz, Carsten C, Kurtcuoglu, Vartan, de Seigneux, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539236/
https://www.ncbi.nlm.nih.gov/pubmed/37096392
http://dx.doi.org/10.1093/ndt/gfad075