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Acetylation reprograms MITF target selectivity and residence time

The ability of transcription factors to discriminate between different classes of binding sites associated with specific biological functions underpins effective gene regulation in development and homeostasis. How this is achieved is poorly understood. The microphthalmia-associated transcription fac...

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Detalles Bibliográficos
Autores principales: Louphrasitthiphol, Pakavarin, Loffreda, Alessia, Pogenberg, Vivian, Picaud, Sarah, Schepsky, Alexander, Friedrichsen, Hans, Zeng, Zhiqiang, Lashgari, Anahita, Thomas, Benjamin, Patton, E. Elizabeth, Wilmanns, Matthias, Filippakopoulos, Panagis, Lambert, Jean-Philippe, Steingrímsson, Eiríkur, Mazza, Davide, Goding, Colin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539308/
https://www.ncbi.nlm.nih.gov/pubmed/37770430
http://dx.doi.org/10.1038/s41467-023-41793-7