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Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions

Non-coding RNAs (ncRNAs) are transcribed throughout the genome and provide regulatory inputs to gene expression through their interaction with chromatin. Yet, the genomic targets and functions of most ncRNAs are unknown. Here we use chromatin-associated RNA sequencing (ChAR-seq) to map the global ne...

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Detalles Bibliográficos
Autores principales: Limouse, Charles, Smith, Owen K., Jukam, David, Fryer, Kelsey A., Greenleaf, William J., Straight, Aaron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539311/
https://www.ncbi.nlm.nih.gov/pubmed/37770513
http://dx.doi.org/10.1038/s41467-023-41848-9