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scBridge embraces cell heterogeneity in single-cell RNA-seq and ATAC-seq data integration

Single-cell multi-omics data integration aims to reduce the omics difference while keeping the cell type difference. However, it is daunting to model and distinguish the two differences due to cell heterogeneity. Namely, even cells of the same omics and type would have various features, making the t...

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Detalles Bibliográficos
Autores principales: Li, Yunfan, Zhang, Dan, Yang, Mouxing, Peng, Dezhong, Yu, Jun, Liu, Yu, Lv, Jiancheng, Chen, Lu, Peng, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539354/
https://www.ncbi.nlm.nih.gov/pubmed/37770437
http://dx.doi.org/10.1038/s41467-023-41795-5