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MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium
The actin-regulated transcription factor MRTF-A represents a central relay in mechanotransduction and controls a subset of SRF-dependent target genes. However, gain-of-function studies in vivo are lacking. Here we characterize a conditional MRTF-A transgenic mouse model. While MRTF-A gain-of-functio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539384/ https://www.ncbi.nlm.nih.gov/pubmed/37770456 http://dx.doi.org/10.1038/s41419-023-06158-4 |