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Melatonin Potentiates Sensitivity to 5-Fluorouracil in Gastric Cancer Cells by Upregulating Autophagy and Downregulating Myosin Light-Chain Kinase

5-Fluorouracil is an effective chemotherapeutic drug for gastric cancer. However, the acquisition of chemotherapeutic resistance remains a challenge in treatment. Melatonin can enhance the therapeutic effect of 5-fluorouracil; however, the underlying mechanisms are not well understood. We investigat...

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Detalles Bibliográficos
Autores principales: Shi, Xiaorui, Li, Hongxia, Dan, Zhangyong, Shu, Chuanlin, Zhu, Rumeng, Yang, Qingling, Wang, Yi, Zhu, Huaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539390/
https://www.ncbi.nlm.nih.gov/pubmed/37779875
http://dx.doi.org/10.7150/jca.85353