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Brucine suppresses proliferation and promotes apoptosis of human cholangiacarcinoma cells via the inhibition of COX2 expression

Aims The aim of this study was to investigate the anti-tumor efficacy of brucine on intrahepatic cholangiocarcinoma (ICC). Methods ICC QBC939 cells were treated with brucine, cell viability, cell cycle and apoptosis were analyzed using CCK-8 and flow cytometry. The expression of COX-2 and apoptosis...

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Detalles Bibliográficos
Autores principales: Kang, Qiang, Zheng, Kai, Jiang, Gai-Ming, Li, Yu-Kai, Liang, Yu-Bo, Geng, Qin, Qian, Chun-Hang, Wang, Qing-Bo, He, Zhong-Yin, Huang, Song-Quan, Yang, Chen, Li, Jing, Li, Yue-Hua, Ke, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539398/
https://www.ncbi.nlm.nih.gov/pubmed/37779869
http://dx.doi.org/10.7150/jca.87514