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Central nervous system disorders after use of dolutegravir: evidence from preclinical and clinical studies
The evaluation of dolutegravir based on available preclinical and clinical studies reveals a risk of central nervous system (CNS) disorders associated with long-term use of the drug. The available literature on the pharmacokinetics of the drug, including its penetration of the blood–brain barrier, w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539422/ https://www.ncbi.nlm.nih.gov/pubmed/37605102 http://dx.doi.org/10.1007/s43440-023-00515-y |