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Central nervous system disorders after use of dolutegravir: evidence from preclinical and clinical studies

The evaluation of dolutegravir based on available preclinical and clinical studies reveals a risk of central nervous system (CNS) disorders associated with long-term use of the drug. The available literature on the pharmacokinetics of the drug, including its penetration of the blood–brain barrier, w...

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Detalles Bibliográficos
Autores principales: Jakimiuk, Alicja, Piechal, Agnieszka, Wiercińska-Drapało, Alicja, Nowaczyk, Alicja, Mirowska-Guzel, Dagmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539422/
https://www.ncbi.nlm.nih.gov/pubmed/37605102
http://dx.doi.org/10.1007/s43440-023-00515-y