CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth

The mammalian target of rapamycin complex1 (mTORC1) is a central regulator of metabolism and cell growth by sensing diverse environmental signals, including amino acids. The GATOR2 complex is a key component linking amino acid signals to mTORC1. Here, we identify protein arginine methyltransferase 1...

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Detalles Bibliográficos
Autores principales: Yin, Shasha, Liu, Liu, Ball, Lauren E., Wang, Yalong, Bedford, Mark T., Duncan, Stephen A., Wang, Haizhen, Gan, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539482/
https://www.ncbi.nlm.nih.gov/pubmed/36995937
http://dx.doi.org/10.1016/j.celrep.2023.112316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539482/
https://www.ncbi.nlm.nih.gov/pubmed/36995937
http://dx.doi.org/10.1016/j.celrep.2023.112316

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